Bojan Kozlevčar, Nina Lah, Simon Makuc, Primož Šegedin, Franc Pohleven
Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, P.O. Box 537,
SI-1001 Ljubljana, Slovenia
Biotechnical Faculty, University of Ljubljana, Rožna dolina, Cesta VIII/34, SI-1000 Ljubljana, Slovenia
During the investigations of fatty acid copper(II) carboxylates with biologically important ligands, several compounds of the composition [Cu2(O2CCnH2n+1)4(urea)] (n = 5 to 11) and [Cu2(O2CC5H11)4(urea)2] were prepared. The molecular structure of the compound [Cu2(O2CC5H11)4(urea)2] was determined by X-ray diffraction analysis. The compounds were characterized by standard physical and chemical methods and tested for their fungal mycelial growth activity with mycelium of two wood decay fungi Trametes versicolor and Antrodia vaillantii. The results of the characterization are in agreement with the values typical for dimeric copper(II) carboxylates. In the electronic spectra the difference between both types of hexanoate compounds is observed, however in vibrational spectra also the differences among the compounds where one molecule of urea is bonded on each dimer were noticed. Significantly higher growth inhibition for the whole series for Antrodia vaillantii was observed.