Primož Škofic, Amalija Golobič, Ljubo Golič and Andrej Petrič

Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, SI-1000 Ljubljana, Slovenia
 

ABSTRACT

Using 4-iodo-N-[2-(1-piperidinyl)ethyl]benzamide (IPAB) as the lead compound we prepared five new 1,2-dicarba-closo-dodecaborane skeleton-containing analogues with the aim of finding new therapeutic agents for Boron Neutron Capture Therapy (BNCT) of malignant melanoma and breast cancer.
Key words: boron neutron capture therapy (BNCT); 1,2-dicarba-closo-dodecaborane; IPAB analogues