Natalija Zajc, Odon Planinšek, Stane Srčič*

Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, SI-1000 Ljubljana, Slovenia
 
 

ABSTRACT

Glassy felodipine samples have been investigated thermoanalytically by means of modulated temperature differential scanning calorimetry (MTDSC). The method advantage of improved signal to noise ratio is confirmed and the glass transition is determined independently from the relaxation phenomena. Experiments with linear saw-tooth modulation with different experimental parameters revealed the strong influence of the modulation period on the data derived. The activation energy of the felodipine glass transition is calculated, introducing different value as determined previously.