A NEW SYNTHESIS OF SUBSTITUTED BENZALDEHYDE N-[(E)-PHENYLMETHYLIDENE]HYDRAZONES

Aleš Obrezaa and Uroš Urlebab

aUniversity of  Ljubljana, Faculty of Pharmacy, Aškerčeva 7, 1000 Ljubljana, Slovenia
bLek d.d., Verovškova 57, 1000 Ljubljana
 

ABSTRACT

Reaction of substituted tert-butyl 2-(phenylmethylidene)-1-hydrazinecarboxylates with gaseous HCl in various anhydrous solvents affords benzaldehyde  N-(phenylmethylidene)-hydrazones in very good yields. A series of substituted benzaldehydes was used for the preparation of this type of compounds. The structure of the resulting compounds was investigated by 1H-NMR, IR and MS spectra.