Elham S. Othman
Department of Chemistry, Faculty of Education, Ain Shams University, Roxy, Cairo 11711, Egypt.†
†Present address: Department of Chemistry, Faculty of Education for Girls, Abha P.O. Box 142, Saudi Arabia Kingdom.
Cyclization of 3-[4-(Benzo[1,3]dioxolylmethylene)-5-oxo-3-pyrazolyl]-4-hydroxy-1-methyl-quinolin-2(1H)-one with certain bifunctional nucleophilic reagents is described. The cyclization reactions led to the formation of many biologically interesting fused heterocyclic systems derived from pyrazolinone and bearing quinolinone moiety e.g. pyrazolopyrazole, isoxazolopyrazole, pyrazolopyrimidine, pyrazolothiazine, pyrazolopyridine, dipyrazolo-pyridine, dipyrazolopyran and many pyrazolopyran derivatives. The structures of all the new products were checked with analytical and spectral methods.