Synthesis of 2-Nitrobenzaldehyde from 2-Nitrotoluene
Faculty of Health and Social Studies, University of South Bohemia, Branišovská 31, 370 05 České Budějovice, Czech Republic. E-mail: email@example.com
Comparison of Arthur Lapworth' one-pot conversion of 2-nitrotoluene to 2-nitrobenzaldehyde with other published synthetic sequences revealed an environmental attractiveness of this reaction. Due optimisation of the procedure was made in order to enhance the safety of this process on a large scale. A highly selective one-pot preparative chemical synthesis of 2-nitrobenzaldehyde from 2-nitrotoluene is described.
Key words: 2-nitrotoluene, 2-nitrobenzaldehyde, 2-propylnitrite