Synthesis, Characterization, Crystal Structures and Fungicidal Activity of Some Copper(II) Carboxylates with 3-Hydroxypyridine
Amalija Golobiča, Ljerka Ožbolta, Franc Pohlevenb, Ivan Lebana and Primož Šegedina
aFaculty of
Chemistry, University of Ljubljana, Aškerčeva 5, P.O.Box 537, 1001 Ljubljana,
Slovenia,
e-mail:primoz.segedin@fkkt.uni-lj.si
bBiotechnical Faculty, University of Ljubljana, Rožna dolina, C. VIII/34,
1000 Ljubljana, Slovenia
Absrtract
Different synthetic routes were applied for preparation of some copper(II)
carboxylates with 3-hydroxypyridine (3-pyOH). Monomeric and dimeric complex of
copper(II) acetate were isolated, [Cu(O2CCH3)2(3-pyOH)2],
1, and [Cu2(O2CCH3)4(3-pyOH)2], 2,
respectively. A covalently linked 2D CuII compounds of general
formula [Cu(O2CR)2(3-pyOH)2]n, were prepared
with benzoate (R=C6H5, 3), hexanoate (R=CH3(CH2)4,
4), and heptanoate (R=CH3(CH2)5, 5) ligands.
The crystal structures of all five compounds were determined by X-ray structure
analysis. The compounds were tested for fungicidal activity against two fungal
species Trametes versicolor and Antrodia vaillantii. Complete growth retardation
for Antrodia vaillantii was noticed for compounds 3, 4, and 5 at concentrations
of 5·10-3 mol L-1, 1·10-3
mol L-1, and 5·10-4
mol L-1, while in the case of Trametes versicolor complete growth
retardation was observed for the same three compounds only at the highest tested
concentration.
Key words: copper(II) carboxylates, 3-hydroxypyridine, fungicidal activity, X-ray structure analysis