Titania (TiO2)-Catalyzed Expedient, Solventless and Mild Synthesis of Bis(Indolyl)Methanes

Mona Hosseini-Sarvari*

Department of Chemistry, Shiraz University, Shiraz 71454, I.R. Iran
Fax: +98(711)2280926;
E-mail: hossaini@susc.ac.ir

Titania (TiO2) is found to be an efficient catalyst for the electrophilic substitution reaction of indoles with aldehydes to afford the corresponding bis(indolyl)methanes in high yields under solvent free conditions.

Keywords: Titania, aldehydes, bis(indolyl)methane, indole