Zirconyl(IV) Chloride – Catalyzed Multicomponent Reaction of β-Naphthols: An Expeditious Synthesis of Amidoalkyl Naphthols
Rahul R. Nagawade and Devanand B. Shinde*
Department of Chemical Technology, Dr. Babasaheb Ambedkar Marathwada University,
Aurangabad – 431004 (M.S.), India.
Tel. 91-240-2400431; E-mail: firstname.lastname@example.org
Zirconyl(IV) chloride is found to be an efficient catalyst for the multicomponent condensation reaction of β-naphthol, aromatic aldehydes and urea or amide to afford the corresponding amidoalkyl naphthols in good yields. The remarkable features of this new procedure are high conversions, shorter reaction times, cleaner reaction profiles and simple experimental and work-up procedures.
Keywords: Zirconyl(IV) chloride, multicomponent reaction, condensation, β-naphthol, aryl aldehyde, urea.