Experimental Determination of Numerical Values of Critical Parameters in the Gatifloxacin
Process Development

Miloš Ružič
Development chemist in the pharmaceutical company Krka, d. d., Novo mesto, R&D Department,
Krka, d. d., Novo mesto, [marje{ka cesta 6, 8000 Novo mesto, Slovenia
E-mail: milos.ruzic@krka.biz

Abstract
A practical example of the determination of critical parameters is presented on the example of the gatifloxacin process development.

Keywords: Critical parameters, numerical determination, gatifloxacin