Daniel Sulikowski and Mieczysław Mąkosza

Institute of Organic Chemistry PAS, ul. Kasprzaka 44/52 01-224 Warszawa, Poland

* Corresponding author: E-mail: icho-s@icho.edu.pl
Fax: 0048 22 632 66 81

Abstract
Diethyl α-(o-nitroaryl)benzylphosphonates readily available via ONSH reaction upon treatment with base undergo cyclization leading to 3-phenyl-2,1-benzisoxazole in high yields. Possible route for this transformation is discussed.

Keywords: Benzisoxazoles, cyclization, heterocycles, nitroarenes, phosphonates