Ali Pourjavadi,* Hamid Salimi, Shahram Barzegar, Bagher Eftekhari-Sis

Polymer Research Laboratory, Department of Chemistry, Sharif University of Technology, P.O. Box 11365-9516, Tehran, Iran.
Fax: +982166005718,
E-mail: purjavad@sharif.edu.

Abstract:
Poly(2-acrylamido-2-methyl propane sulphonic acid) crosslinked with N,N’-methylene bisacrylamide catalyses efficiently the three component condensation reaction of an aromatic aldehyde, β-ketoester and urea in refluxing ethanol to afford the corresponding dihydropyrimidinones in high yield.

Keywords: Biginelli reaction, three-component reaction, polymeric catalyst