A Facile One-Pot Synthesis of Amino Furans Using Trans-Cinnamaldehyde in the Presence of Nucleophilic Isocyanides

Sakineh Asghari* and Mohammad Qandalee
Department of Chemistry, University of Mazandaran, P. O. Box 453, Babolsar, Iran
E-mail: s.asghari@umz.ac.ir

The 1 : 1 reactive intermediate generated by the addition of alkyl isocyanide to dialkyl acetylenedicarboxylates was
trapped by trans-cinnamaldehyde to yield polyfunctionalized furan rings

Keywords: Tert-butylisocyanide, dialkyl acetylenedicarboxylate, trans-cinnamaldehyde