Synthesis of Novel Macrocyclic Lactam Based Receptors for Alkali or Transition Metal Cations and Cr2O7 2– Anions

Şeref Ertul,1,* Hacı Ahmet Tombak,1,2 Mevlüt Bayrakcı1 and Orhan Merter1

1 Department of Chemistry, Selc¸uk University, 42031, Konya, Turkey
2 Department of Nuclear Medicine, Selc¸uk University, 42031, Konya, Turkey
* Corresponding author: E-mail:,

The article describes the syntheses and extraction properties of new lactam ionophores. These lactam derivatives were easily synthesized via aminolysis of 2,2’-methylenebis(4-chlorophenol) dimethylester or its corresponding acyl chloride with corresponding diamine compounds in THF or methanol-dichloromethane solvent systems in one step, respectively. The extraction studies of lactam ionophores were performed toward dichromate anion and alkaline and transition metal cations such as Li+, Na+, K+, Co2+, Hg2+ and Pb2+. All the structures of the ionophores were confirmed by spectroscopic techniques and elemental analysis.

Keywords: Lactam, chromate extraction, picrate extraction, liquid-liquid extraction